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Original Collection by Dr. Scholl's Scout High Sandals iKinP
Original Collection by Dr. Scholl's Scout High Sandals

International Art and Culture

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Matthew Barney and Jonathan Bepler. "River of Fundament," 2014. Production still, courtesy of Gladstone Gallery, New York and Brussels, © Matthew Barney, photo by Hugo Glendinning.

Matthew Barney: River of Fundament September 13, 2015 – January 18, 2016 Museum of Contemporary Art, Los Angeles 250 South Grand Avenue, Los Angeles, CA 90012

Much has been made of the meaninglessness and conjoining over-extravagance of Matthew Barney’s newest film and sculpture exhibition, River of Fundament , now on view at MOCA in Los Angeles, the only U.S. iteration of the traveling exhibition. Where his acclaimed video opus, The Cremaster Cycle , was released in stages over the course of several years and included differing locales and odd turns on in-depth, abstruse plot twists, River of Fundament is presented all in one gluttonous gulp of a sitting: a six-hour film with two brief intermissions. Not only does the film’s duration alone make it overwhelming to digest, but furthermore, the term digest has perhaps rarely been so apropos, as the film’s endpoint of fecal matter is at the crux not only of its conceptual framework but more viscerally, its visual referents. With all this buzz of the film’s unnecessary grotesquery, it is easy to approach the first of many hours of sitting in the black box at MOCA with a somewhat indifferent attitude, expecting shock value to rule and actual meaning to stagger meekly behind, trying to catch up. This is not entirely untrue, but regardless, it is nonetheless refreshing to see captivating imagery toppled upon itself so densely, even if much of one’s eye-widening is only due to the subject matter’s obvious depravity and spectacle therein.

Matthew Barney and Jonathan Bepler. “River of Fundament,” 2014. Production still, courtesy of Gladstone Gallery, New York and Brussels, © Matthew Barney, photo by Chris Winget.

Within the first minutes of the film, Barney’s character emerges from the shit-filled “river” (which looks much more like just a dank, still, underground puddle of clay-water, which it in fact was), grabs a log of poo out of a toilet with his bare hands and covers it in gold leaf, and then proceeds to turn away from an older, equally filthy man whose penis and the gold-covered turd suddenly appear to be one and the same, in order to let him penetrate him. On the one hand it is annoying that anal sex between two men should be considered such a shocker within contemporary video art, but, on the other hand, it is still certainly more scintillating to look at, much less intellectually or emotionally consider, than, let’s say, a putty-colored abstract painting, the type of which still dominates many a vast white cube. This is not to dispel the ‘trumors’ that Barney’s signature tropes of grandiosity persist throughout Fundament , because they are undeniably there and they are often just as infuriating in their pseudo-intellectual tone as ever. However, as one has always been able to find buried deep within Barney’s amass of seemingly non-sequitur symbols and unusually manifested characters, there are clearly important nods and dissections of moments in history and literature that at times come to the film’s fuzzy fore. Not only that, but Fundament feels far less like a sculpture in video form, as Barney has in the past described his work on screen, and much more like a proper cinematic endeavor, with dialog (of sorts), formal readings and less formal liftings of seminal texts by renowned American authors including Hemingway, Burroughs and Whitman, and cameo performances by major actors, musicians and other artists including Paul Giamatti, Maggie Gyllenhaal, the late Elaine Stritch, Fran Lebowitz, Debbie Harry and Lawrence Weiner, to name just a few.

Ready to go? Get to the heart of Portugal with one of Lonely Planet's in-depth, award-winning guidebooks.

Lisbon to Sintra and Cascais Small-Group Tour with Pena Park

Just a short trip away from Lisbon are the beautiful towns of Sintra and Cascais. Start your tour with the journey to Sintra. Visit Pena Park, where you will be amazed by the variety of trails, trees and other plants. Head to the Queen's Throne for an amazing view of the Pena National Palace (Palacio da Pena) and the Atlantic Ocean. Next, feel like Portuguese royalty as you enter the romantic Pena National Palace at the top of Sintra Mountain. See the Great Triton, the guardian of the palace, inspired by Manueline art. Inside the palace, admire the attention to detail in the bedrooms of the king and queen and the Arab Room. Leave the palace and follow your guide to the historical center of Sintra, where you’ll have free time to explore the town, to visit Sintra National Palace (where the Portuguese royalty of the 15th and 16th centuries used to spend the summer months) or have some lunch (own expense). For dessert, try a travesseiro or a queijada, two delicious local pastries. Next, admire the landscape of Sintra Natural Parkon the way to the next stop. Enjoy a photo opportunity at the cliffs of Roca Cape (Cabo da Roca), the westernmost point of Europe, and visit the surfer's paradise of Guincho Beach. Pass the cliff at Hell’s Mouth (Boca do Inferno), before stopping to stretch your legs along Cascais’ bay. Wander around the center of Cascais, a former fishing village and today a popular holiday spot. Follow your guide through narrow alleyways and see the traditional Portuguese white houses or enjoy some time relaxing at the beach. On the drive back to Lisbon where your tour concludes, soak up the scenic views along the Atlantic coast and in the town of Estoril.

Douro Valley Wine Tasting Tour, Lunch, River Cruise Option

Leave your Porto hotel in the morning and travel inland to the Douro Valley by air-conditioned minivan. After a journey of roughly 90 minutes, you’ll arrive in Peso da Régua, the valley’s capital, where you'll stop to soak in your first impression of the valley. If you’ve opted to include a boat ride with your tour, you’ll be dropped off in Pinhão for a leisurely 1-hour cruise along the Douro River. Aboard a rabelo boat — a traditional cargo boat native to this region — travel up the Tua river tributary and pass by Quinta da Romaneira before returning back to Pinhão. Alternatively, you can choose to spend time exploring the beautiful village of Pinhão independently. A highlight is the Pinhão train station, known for its pretty blue-and-white tile murals that depict the scenic Douro landscapes and vineyard workers. Stop to enjoy a traditional Portuguese lunch with specialties accompanied with local wine.Continue your tour to two family-run wine estates nestled in the gloriously remote countryside, a setting that offers a glimpse into the way of life in Douro. Learn about local winemaking as you sample various ports and wines, and then explore the shop for treats to take home with you.After a full day experiencing the Douro Valley, relax on the drive back to your Porto hotel, arriving in the early evening.

Lisbon Small-Group Walking Tour with Food and Wine Tastings

Begin your walking tour of Lisbon at Restauradores Square, the perfect spot to hear a bit of Lisbon history. Your informative local guide will tell you about Portugal’s Restoration years and what effect this period had on the places you will see during your three- to four-hour tour. Get on the move by exploring the magnetic neighborhood of Mouraria, a melting pot of cultures and one of the city’s most modern areas, where tourists don't often venture. Pass small churches, mosques and shops selling goods from far-away places. Learn about Fado, Portugal's own music genre that was declared a UNESCO Intangible Cultural Heritage, as you walk past the birthplace of the legendary Maria Severa (Fado’s first superstar). Next, visit a small, hidden bakery where traditional pastries and coffee will provide you with a tasty treat and another insight into local life in Lisbon. Then, walk past the beautiful Gothic-style Rossio train station, visit Rossio Square (Lisbon’s main square) and find out how much the city has changed since the devastating earthquake of 1755 that destroyed 85 percent of the city. Continue visiting historical landmarks, churches and other attractions before stopping again for a taste of Portuguese cheese and locally made marmalade. Then see the picturesque Carmo Square with its beautiful Carmo Convent, and walk up to the top of the famous Santa Justa funicular to enjoy wonderful views.Walk through the trendy old district of Chiado, an aristocratic quarter home to small shopping centers, boutiques, historical cafes and old bookstores. Compare it with Barrio Alto, Lisbon’s bohemian district and the center for nightlife. Then take a short ferry ride on the River Tagus toward the picturesque Cacilhas, where Portuguese green wine and freshly caught seafood awaits. Enjoy magnificent views from the south bank before returning to central Lisbon.

Lisbon to Fatima, Nazare, and Obidos Small-Group Day Tour

While you are in Lisbon, head north on a day trip to the beautiful villages of Fátima, Nazaré and Óbidos. Get comfortable in an air-conditioned vehicle as you start your journey toward the town of Fátima, a once-sleepy rural village that became an important pilgrimage site when three shepherd children reported apparitions of the Virgin Mary in 1917. Visit the Sanctuary of Fatima, a basilica that honors the apparition and attracts millions of Catholic pilgrims every year who go to pay their respects to the shrine.Next, visit the 14th-century Batalha Monastery, a UNESCO World Heritage Site that illustrates the rich artistic heritage of the late 1300s. Discover the impressive royal burial site at the basilica’s Founder’s Chapel, where King João I, Queen Philippa of Lancaster and their son Prince Henry the Navigator were buried.Take a short break for lunch (own expense) in Nazaré, a quaint fishing town famous for its variety of restaurants and cafes. A popular summer retreat for the Portuguese, the village offers an interesting insight into local life. Next, head to the Nazaré cliffs and continue through the picturesque villages of Foz do Arelho and São Martinho do Porto. Admire views of agricultural fields and the Atlantic Ocean as you drive along the dramatic, cliff-lined coast.Finally, make your way to the medieval village of Óbidos. Founded in 208 BC, Óbidos is commonly known in Portugal as the 'wedding present town', as it was a gift from King Dinis to Queen Isabel on their wedding day in 1282. Follow your guide to one of the numerous wine shops and sample the Ginja liqueur, and then enjoy free time to explore the village’s medieval fortress, narrow streets, colorful houses and Gothic doorways and windows decorated with flowerpots and dazzling tiles. Grab a snack or browse around the tiny shops that offer a varied collection of beautiful handmade ceramic art before making your way back to Lisbon.

Lisbon Highlights Guided Walking Tour with Tram Ride

Your first stop on your guided walking tour of Lisbon is Rossio Square, the heart of the old and new Lisbon. The square was built in the 19th century and is paved with typical Portuguese cobblestones in the shape of waves. Next, visit Restauradores Square, where an obelisk stands tall, commemorating Portugal’s independence from Spain in 1640. From here, admire Liberdade Avenue, the Eden Theatre (one of the best examples of Portuguese Art Deco), and the 18th-century Foz Palace. Marvel at the intricate Neo-Manueline architecture of Rossio Central Station, which connects the city to Sintra through a 1.61-mile-long (2.6 km) tunnel and is considered to be one of the most important engineering works of Portugal from the 19th century.Next, learn about the Carnation Revolution as you visit beautiful Carmo Square, the very place where Portugal’s old dictatorial regime fell in 1974 after 48 years and where the Carmelite's Carmo Convent is located. Then walk through the elegant Chiado neighborhood, with its old cafés, boutiques, theaters and bookstores. Spend some time in this aristocratic quarter, one of the most interesting pedestrian areas in Lisbon, before enjoying a short trip on one of Lisbon’s vintage trams (fare included).When you get off the tram, wander through the small squares, twisting streets and blind alleys where the roofs almost touch each other of Alfama, a Moorish neighborhood and the oldest district in Lisbon. This is the birthplace of Fado, Portugal's own musical genre. Learn about this type of music as you pass the Fado Museum and some hidden Fado restaurants.Then admire the beauty of Sé de Lisboa cathedral, the city’s oldest church. End your tour in Commerce Square (Praça do Comércio), one of Europe’s largest squares that was for centuries a reception hall for visitors arriving by sea.

Lisbon Small-Group Gourmet Portuguese Food and Wine Tour

On this small-group gourmet tour of Lisbon, wind your way through the city’s beautiful streets and get a taste for the local cuisine with stops at traditional restaurants and bars, sampling delicacies like petiscos.Find out about Lisbon’s great cafés, such as the 18th-century Café Nicola — one of Lisbon’s most literary cafés and a place for tertúlias — and discover why Pastelaria Suiça is another landmark of Rossio. Try the famous Portuguese Codfish Cake with a glass of refreshing Green Wine, and learn about the Bairro Alto quarter. In the 20th century, the Bairro Alto became Lisbon’s bohemian quarter and the center for nightlife, full of bars, restaurants, and nightclubs.Stop at an atmospheric wine bar in the Bairro Alto for tapas and a glass of local white wine. Visit one of the most famous restaurants in Lisbon, Cervejaria da Trindade (brewery), famous for its seafood and steaks.Then it’s on to the steps of Calçada do Duque, two areas with a great variety of restaurants and nice views of the city. Learn the secrets of success at Manteigaria Silva, open since 1908, and see the delicious products on display, such as sausages, hams, and cheeses. Here, learn the history of Port, Portugal’s famous fortified wine, as you try it with a piece of delicious São Jorge cheese. Later, compare your Port with a typical Portuguese cherry brandy at A Ginjinha, and try a bacalhaufish cake at Tendinha.Continue to Portas de Santo Antão Street, one of the city’s main entrances, the Gates of Santo Antão. Finish your gourmet tour with a light meal (bread, cheese, sausage, and other local products) and a glass of Alentejo wine at the Neo-Moorish Casa do Alentejo, a 17th-century palace with one of the most intriguing interiors in the city.

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Reviewed by: Sid Dajani, 20 Jul 2017

Warfarin - an anticoagulant

In this article

About warfarin

Warfarin is an anticoagulant , which means that it increases the time it takes for your blood to clot. It works by reducing the effects of vitamin K, which is a vitamin your body uses in the process of blood-clotting.

Warfarin is used to prevent unwanted clots from forming if you have a condition that puts you at risk of this happening, such as atrial fibrillation . It is also used to prevent any clots that may have already formed in the blood vessels of your legs, lungs or heart from becoming larger and causing problems.

Warfarin is currently the most prescribed anticoagulant although newer anticoagulants are increasingly being prescribed.

Before taking warfarin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking warfarin it is important that your doctor knows:

How to take warfarin

Getting the most from your treatment

Can warfarin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with warfarin - the most common are bleeding and bruising. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

How to store warfarin

Important information about all medicines

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Further reading and references

; Ranbaxy (UK) Limited, The electronic Medicines Compendium. Dated January 2017.

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